Proven efficacy

Action that sets this tablet apart

1. Penetrates the micro-porosities of the appliance

2. Cleanses the appliance in depth

Single Use

 

A single use of NitrAdine® is effective in eliminating certain species of microorganisms, including selected viruses (Herpes Simplex), in vitro. (Quintessence Int 2004, Prof. R. Thomas Glass, et al.) 

A novel disinfecting formula for the maintenance of oral medical devices... (Journal of Applied Microbiology, Prof. T. Coenye)

NitrAdine® Clinical Performance on Dentures

Introduction

Denture-induced stomatitis is an inflammatory lesion of the denture bearing mucosa that affects approximately 50% of patients wearing maxillary complete dentures, and has a multifactor etiology. The presence of denture biofilm is an important etiologic factor for this disease. Biofilm found on dentures consists of a complex mixture of fungi and bacteria and desquamated epithelial cells.

This biofilm act as a protective reservoir for oral microorganisms and Candida albicans and other species of yeast found in biofilm have been reported as important agents for the installation, maintenance and exacerbation of denture stomatitis. Scanning electron microscopic evaluation of dentures retrieved from patients suffering from denture stomatitis demonstrates that Candida biofilm not only colonizes the surface, but also penetrate the cracks and imperfections of the denture material.

The efficacy of several dentures cleansers has been clinically evaluated in a number of approaches, and commercially available denture cleansing products are generally not very efficient in denture biofilm control.

Results

study1_graph001

Conclusion

Microbial denture biofilm counts were substantially higher in the control method when compared with the treatment based on denture brushing and the immersion in Nitradine Disinfecting tablets.

Therefore, these tablets should be recommended as a routine denture maintenance method for the prevention of the development of microbial biofilm induced denture stomatitis.